• Highlights
• Contents
• Indications and Usage
• Dosage and Administration
• Dosage Forms and Strengths
• Contraindications

• Warnings and Precautions
• Adverse Reactions
• Drug Interactions
• Use in Specific Populations
• Description

• Clinical Pharmacology
• Nonclinical Toxicology
• Clinical Studies
• References
• How Supplied/
  Storage and Handling

15 REFERENCES

1. Chapman WC, Singla N, Genyk Y, McNeil JW, Renkens Jr KL, Reynolds TC, Murphy A, Weaver FA. A Phase 3, Randomized, Double-Blind Comparative Study of the Efficacy and Safety of Topical Recombinant Human Thrombin and Bovine Thrombin in Surgical Hemostasis. J Am Coll Surg 2007;205:256-265.
2. Singla NK, Ballard JL, Moneta G, et al. A Phase 3b Open-Label, Single-Group Immunology and Safety Study of Topical Recombinant Thrombin (rThrombin) in Surgical Hemostasis. J Am Coll Surg 2009;209:68-74.
3. Greenhalgh DG, Gamelli RL, Collins J, et al. Recombinant Thrombin: Safety and Immunogenicity in Burn Wound Excision and Grafting. J Burn Care Res 2009;30:371-379.